Synthesis and Degradation of Ketone Bodies (Gallus gallus)

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Curation Tags

Description

Ketone bodies are three water-soluble compounds that are produced as by-products when fatty acids are broken down for energy in the liver and kidney. They are used as a source of energy in the heart and brain. In the brain, they are a vital source of energy during fasting.

Source: Wikipedia


Comments

GenMAPP notes 
Ketogenesis (Human)
GenMAPP remarks 
Adapted from KEGG
HomologyConvert 
This pathway was inferred from Homo sapiens pathway WP311(r21335) with a 55% conversion rate.

Bibliography

  1. Fukao T, Lopaschuk GD, Mitchell GA; ''Pathways and control of ketone body metabolism: on the fringe of lipid biochemistry.; ''Prostaglandins Leukot Essent Fatty Acids, 2004 - PubMed

Categories

History

View all
CompareRevisionActionTimeUserComment
35392view09:38, 12 February 2010Thomasfixed connections
35383view09:25, 12 February 2010Thomasadded literature, fixed metabolite xrefs
35376view09:17, 12 February 2010ThomasModified description
33880view17:53, 9 December 2009MaintBotAutomatic update of empty xrefs
30353view20:53, 29 July 2009MaintBotNew pathway

Pathway Info

DataNodes

View all 10 DataNodes

Name Type Backpage Header Database reference
Acetoacetyl-CoAMetabolite1420-36-6 (CAS)
ACAT1GeneProductACAT1418968 (Entrez Gene)
HMGCS2GeneProductHMGCS2424380 (Entrez Gene)
3-Hydroxy-butyrateMetabolite3037032 (PubChem)
HMGCLGeneProductHMGCL396316 (Entrez Gene)
Acetyl-CoAMetabolite72-89-9 (CAS)
OXCT1GeneProductOXCT1427190 (Entrez Gene)
3-Hydroxy-3-methylglutaryl-CoAMetabolite1553-55-5 (CAS)
BDH1GeneProductBDH1424891 (Entrez Gene)
AcetoacetateMetabolite6971017 (PubChem)
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