Complement Activation, Classical Pathway (Homo sapiens)
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Description
The complement system is a biochemical cascade that helps, or “complements”, the ability of antibodies to clear pathogens from an organism. It is part of the immune system called the innate immune system that is not adaptable and does not change over the course of an individual's lifetime. However, it can be recruited and brought into action by the adaptive immune system. The Classical pathway of activation of the complement system is a group of blood proteins that mediate the specific antibody response. [source: Wikipedia)
Bibliography
- Brook E, Herbert AP, Jenkins HT, Soares DC, Barlow PN; ''Opportunities for new therapies based on the natural regulators of complement activation.; ''Ann N Y Acad Sci, 2005 - PubMed
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Pathway Info
DataNodes
| View all 18 DataNodes |
| Name | Type | Backpage Header | Database reference |
|---|---|---|---|
| C9 | GeneProduct | C9 | complement component 9 | 735 (Entrez Gene) |
| C6 | GeneProduct | C6 | complement component 6 | 729 (Entrez Gene) |
| C1QB | GeneProduct | C1QB | complement component 1 q subcomponent ... | 713 (Entrez Gene) |
| C1QA | GeneProduct | C1QA | complement component 1 q subcomponent ... | 712 (Entrez Gene) |
| C1QG | GeneProduct | C1QG | complement component 1 q subcomponent ... | 714 (Entrez Gene) |

