Acetylcholine Synthesis (Homo sapiens)
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Description
Acetylcholine is an important neurotransmitter. It can be rapidly released in the synaptic cleft upon activation of the neuron. In the synaptic cleft the compound is degraded rapidly into choline and acetate, this is essential for proper neuronal functioning. Choline and Acetate are taken up into the cytosol and recycled for the next activation.
Bibliography
- Blusztajn JK, Wurtman RJ; ''Choline and cholinergic neurons.; ''Science, 1983 - PubMed
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DataNodes
| View all 17 DataNodes |
| Name | Type | Backpage Header | Database reference |
|---|---|---|---|
| Phosphatidylcholine | Metabolite | HMDB00564 (HMDB) | |
| PDHA2 | GeneProduct | PDHA2 | pyruvate dehydrogenase (lipoamide) alph... | 5161 (Entrez Gene) |
| Phosphorylcholine | Metabolite | HMDB01565 (HMDB) | |
| PEMT | GeneProduct | PEMT | phosphatidylethanolamine N-methyltransfe... | 10400 (Entrez Gene) |
| Acetyl CoA | Metabolite | 72-89-9 (CAS) |

