G13 Signaling Pathway (Homo sapiens)

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Description

The G13 subunit is an alpha unit of heterotrimeric G proteins that regulates cell processes through the use of guanine nucleotide exchange factors. G13 regulates actin cytoskeletal remodeling in cells and is essential for receptor tyrosine kinase-induced migration of fibroblast and endothelial cells.

Source: Wikipedia


Bibliography

  1. Neves SR, Ram PT, Iyengar R; ''G protein pathways.; ''Science, 2002 - PubMed

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History

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CompareRevisionActionTimeUserComment
35408view10:24, 12 February 2010ThomasModified description
35407view10:19, 12 February 2010Thomasfixed labels / lines, added literature
32456view17:24, 15 August 2009MaintBotFixed text labels
32138view13:57, 14 August 2009MaintBotFixed group labels
31473view21:20, 13 August 2009MaintBotFixed text labels
21780view11:32, 14 November 2008MaintBot[[Pathway:Homo sapiens:G13 Signaling Pathway]] moved to [[Pathway:WP524]]: Moved to stable identifier
14478view00:07, 23 May 2008KhanspersAdded connectors, groups, metabolites
14476view23:58, 22 May 2008KhanspersPeriodical save, work in progress
12989view11:00, 17 May 2008MaintBotSticky edges patch by Sjoerd
12580view01:45, 16 May 2008KushidatSpecify description
12573view01:14, 16 May 2008KushidatPeriodical save, work in progress
12563view01:04, 16 May 2008KushidatPeriodical save, work in progress
12556view00:44, 16 May 2008KushidatPeriodical save, work in progress
8064view13:46, 7 January 2008MaintBot[[Pathway:Human:G13 Signaling Pathway]] moved to [[Pathway:Homo sapiens:G13 Signaling Pathway]]: Renaming species
7654view16:07, 18 December 2007MaintBotfixed category names
7229view12:41, 4 November 2007MaintBotAdded categories to GPML
6320view22:17, 22 May 2007A.Chowgpml file for [[Human:G13_Signaling_Pathway]]

Pathway Info

DataNodes

View all 38 DataNodes

Name Type Backpage Header Database reference
RHPN2GeneProductRHPN2 | rhophilin Rho GTPase binding protein 2...85415 (Entrez Gene)
ROCK2GeneProductROCK2 | Rho-associated coiled-coil containing ...9475 (Entrez Gene)
GNA13GeneProductGNA13 | guanine nucleotide binding protein (G p...10672 (Entrez Gene)
LIMK1GeneProductLIMK1 | LIM domain kinase 13984 (Entrez Gene)
ARHGEF1GeneProductARHGEF1 | Rho guanine nucleotide exchange facto...9138 (Entrez Gene)
PIK3CDGeneProductPIK3CD | phosphoinositide-3-kinase catalytic ...5293 (Entrez Gene)
RHOAGeneProductRHOA | ras homolog gene family member A387 (Entrez Gene)
CDC42GeneProductCDC42 | cell division cycle 42 (GTP binding pro...998 (Entrez Gene)
PIK3R2GeneProductPIK3R2 | phosphoinositide-3-kinase regulatory ...5296 (Entrez Gene)
RPS6KB1GeneProductRPS6KB1 | ribosomal protein S6 kinase 70kDa p...6198 (Entrez Gene)
DIAPH1GeneProductDIAPH1 | diaphanous homolog 1 (Drosophila)1729 (Entrez Gene)
PIK3CAGeneProductPIK3CA | phosphoinositide-3-kinase catalytic ...5290 (Entrez Gene)
PFN1GeneProductPFN1 | profilin 15216 (Entrez Gene)
CFL1GeneProductCFL1 | cofilin 1 (non-muscle)1072 (Entrez Gene)
PIP5K2AGeneProductPIP5K2A | phosphatidylinositol-4-phosphate 5-ki...5305 (Entrez Gene)
CALM1GeneProductCALM1 | calmodulin 1 (phosphorylase kinase del...801 (Entrez Gene)
MAPK10GeneProductMAPK10 | mitogen-activated protein kinase 105602 (Entrez Gene)
WASGeneProductWAS | Wiskott-Aldrich syndrome (eczema-thromboc...7454 (Entrez Gene)
PKN1GeneProductPKN1 | protein kinase N15585 (Entrez Gene)
IQGAP2GeneProductIQGAP2 | IQ motif containing GTPase activating ...10788 (Entrez Gene)
MYBPHGeneProductMYBPH | myosin binding protein H4608 (Entrez Gene)
ROCK1GeneProductROCK1 | Rho-associated coiled-coil containing ...6093 (Entrez Gene)
PPP1CBGeneProductPPP1CB | protein phosphatase 1 catalytic subun...5500 (Entrez Gene)
SH3MD2GeneProductSH3MD2 | SH3 multiple domains 257630 (Entrez Gene)
ARHGDIBGeneProductARHGDIB | Rho GDP dissociation inhibitor (GDI) ...397 (Entrez Gene)
PIK3CBGeneProductPIK3CB | phosphoinositide-3-kinase catalytic ...5291 (Entrez Gene)
RAC1GeneProductRAC1 | ras-related C3 botulinum toxin substrate...5879 (Entrez Gene)
CFL2GeneProductCFL2 | cofilin 2 (muscle)1073 (Entrez Gene)
MAP3K4GeneProductMAP3K4 | mitogen-activated protein kinase kinas...4216 (Entrez Gene)
RTKNGeneProductRTKN | rhotekin6242 (Entrez Gene)
PAK3GeneProductPAK3 | p21 (CDKN1A)-activated kinase 35063 (Entrez Gene)
ARHGDIGGeneProductARHGDIG | Rho GDP dissociation inhibitor (GDI) ...398 (Entrez Gene)
MYL1GeneProductMYL1 | myosin light polypeptide 1 alkali; ske...4632 (Entrez Gene)
TNK2GeneProductTNK2 | tyrosine kinase non-receptor 210188 (Entrez Gene)
CITGeneProductCIT | citron (rho-interacting serine/threonine...11113 (Entrez Gene)
WASLGeneProductWASL | Wiskott-Aldrich syndrome-like8976 (Entrez Gene)
IQGAP1GeneProductIQGAP1 | IQ motif containing GTPase activating ...8826 (Entrez Gene)
p140 Sra-1GeneProduct (SwissProt)
Retrieved from "http://wikipathways.org/index.php/Pathway:WP524"
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