Non-homologous end joining (Homo sapiens)
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Description
(From http://en.wikipedia.org/wiki/Non-homologous_end_joining) Non-homologous end joining (NHEJ) is a pathway that repairs double-strand breaks in DNA. NHEJ is referred to as "non-homologous" because the break ends are directly ligated without the need for a homologous template, in contrast to homologous recombination, which requires a homologous sequence to guide repair. NHEJ is evolutionarily conserved throughout all kingdoms of life and is the predominant double-strand break repair pathway in mammalian cells.
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DataNodes
| View all 10 DataNodes |
| Name | Type | Backpage Header | Database reference |
|---|---|---|---|
| Nbs1 ? | GeneProduct | ||
| DNA-PKcs | GeneProduct | ENSG00000121031 (Ensembl Human) | |
| Ku80 | GeneProduct | ENSG00000079246 (Ensembl Human) | |
| MRE11A | GeneProduct | ENSG00000020922 (Ensembl Human) | |
| Ku70 | GeneProduct | ENSG00000196419 (Ensembl Human) |

