MAPK Cascade (Homo sapiens)

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Contents 1 Curation Tags 2 Description 3 Bibliography 4 Categories 5 History 6 Pathway Info 6.1 DataNodes

Curation Tags

Description

Bibliography

1. Orton RJ, Sturm OE, Gormand A, Wolch W, Gilbert DR; ''Computational modelling reveals feedback redundancy within the epidermal growth factor receptor/extracellular-signal regulated kinase signalling pathway.; ''IET Syst Biol, 2008 - PubMed

Categories

History

View all

Compare	Revision	Action	Time	User	Comment
	35455	view	11:51, 12 February 2010	Michiel	Added ref
	34450	view	18:21, 10 December 2009	MaintBot	Automatic update of empty xrefs
	32427	view	17:11, 15 August 2009	MaintBot	Fixed text labels
	32090	view	13:42, 14 August 2009	MaintBot	Fixed group labels
	21570	view	11:32, 14 November 2008	MaintBot	[[Pathway:Homo sapiens:MAPK Cascade]] moved to [[Pathway:WP422]]: Moved to stable identifier
	14694	view	19:37, 23 May 2008	Khanspers	Added connectors
	14692	view	19:36, 23 May 2008	Khanspers	Periodical save, work in progress
	13082	view	11:14, 17 May 2008	MaintBot	automated metabolite conversion
	12928	view	10:41, 17 May 2008	MaintBot	Sticky edges patch by Sjoerd
	8242	view	13:46, 7 January 2008	MaintBot	[[Pathway:Human:MAPK Cascade]] moved to [[Pathway:Homo sapiens:MAPK Cascade]]: Renaming species
	7741	view	16:14, 18 December 2007	MaintBot	fixed category names
	7274	view	12:41, 4 November 2007	MaintBot	Added categories to GPML
	19505	view	22:18, 22 May 2007	I.Reyes	gpml file for [[Human:MAPK_Cascade]]
	6349	view	22:18, 22 May 2007	Nsalomonis	gpml file for [[Human:MAPK_Cascade]]

Pathway Info

DataNodes

View all 32 DataNodes

Name	Type	Backpage Header	Database reference
GDP	Metabolite		146-91-8 (CAS)
MAPK10	GeneProduct	MAPK10 | mitogen-activated protein kinase 10	5602 (Entrez Gene)
PLCB3	GeneProduct	PLCB3 | phospholipase C beta 3 (phosphatidylin...	5331 (Entrez Gene)
MAP2	GeneProduct	MAP2	4133 (Entrez Gene)
RASA3	GeneProduct	p21/ras activ.	22821 (Entrez Gene)
JUN	GeneProduct	JUN | v-jun sarcoma virus 17 oncogene homolog (...	3725 (Entrez Gene)
HRAS	GeneProduct	HRAS | v-Ha-ras Harvey rat sarcoma viral oncoge...	3265 (Entrez Gene)
MAPK1	GeneProduct	MAPK1 | mitogen-activated protein kinase 1	5594 (Entrez Gene)
NRAS	GeneProduct	NRAS | neuroblastoma RAS viral (v-ras) oncogene...	4893 (Entrez Gene)
MAP2K7	GeneProduct	MAP2K7 | mitogen-activated protein kinase kinas...	5609 (Entrez Gene)
RRAS	GeneProduct	RRAS | related RAS viral (r-ras) oncogene homol...	6237 (Entrez Gene)
MAPK14	GeneProduct	MAPK14 | mitogen-activated protein kinase 14	1432 (Entrez Gene)
KRAS	GeneProduct	KRAS | v-Ki-ras2 Kirsten rat sarcoma viral onco...	3845 (Entrez Gene)
MAPK12	GeneProduct	MAPK12 | mitogen-activated protein kinase 12	6300 (Entrez Gene)
RAF1	GeneProduct	RAF1 | v-raf-1 murine leukemia viral oncogene h...	5894 (Entrez Gene)
SIPA1	GeneProduct	SIPA1	6494 (Entrez Gene)
ARAF	GeneProduct	ARAF | v-raf murine sarcoma 3611 viral oncogene...	369 (Entrez Gene)
MBP	GeneProduct	mbp	4155 (Entrez Gene)
BRAF	GeneProduct	BRAF | v-raf murine sarcoma viral oncogene homo...	673 (Entrez Gene)
ELK1	GeneProduct	ELK1 | ELK1 member of ETS oncogene family	2002 (Entrez Gene)
MAP3K1	GeneProduct	MAP3K1 | mitogen-activated protein kinase kinas...	4214 (Entrez Gene)
MAP2K4	GeneProduct	MAP2K4 | mitogen-activated protein kinase kinas...	6416 (Entrez Gene)
MAP3K2	GeneProduct	MAP3K2 | mitogen-activated protein kinase kinas...	10746 (Entrez Gene)
MAP2K6	GeneProduct	MAP2K6 | mitogen-activated protein kinase kinas...	5608 (Entrez Gene)
MAP3K3	GeneProduct	MAP3K3 | mitogen-activated protein kinase kinas...	4215 (Entrez Gene)
MAP2K3	GeneProduct	MAP2K3 | mitogen-activated protein kinase kinas...	5606 (Entrez Gene)
MAP2K1	GeneProduct	MAP2K1 | mitogen-activated protein kinase kinas...	5604 (Entrez Gene)
MAP3K12	GeneProduct	MAP3K12 | mitogen-activated protein kinase kina...	7786 (Entrez Gene)
MAP2K2	GeneProduct	MAP2K2 | mitogen-activated protein kinase kinas...	5605 (Entrez Gene)
RapGAPII	GeneProduct	RapGAPII	(SwissProt)
MAPK3	GeneProduct	MAPK3 | mitogen-activated protein kinase 3	5595 (Entrez Gene)
GTP	Metabolite		2564-35-4 (CAS)