miR-148a/miR-31/FIH1/HIF1α-Notch signaling in glioblastoma (Homo sapiens)

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Description

miR-148a and miR-31 target the factor inhibiting hypoxia (FIH1) to promote downstream HIF1α and Notch signaling

Quality Tags

Ontology Terms

 

Bibliography

  1. Wong HK, Fatimy RE, Onodera C, Wei Z, Yi M, Mohan A, Gowrisankaran S, Karmali P, Marcusson E, Wakimoto H, Stephens R, Uhlmann EJ, Song JS, Tannous B, Krichevsky AM; ''The Cancer Genome Atlas Analysis Predicts MicroRNA for Targeting Cancer Growth and Vascularization in Glioblastoma.''; Mol Ther, 2015 PubMed

History

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CompareRevisionActionTimeUserComment
87762view09:58, 25 July 2016RyanmillerOntology Term : 'glioma pathway' added !
87735view09:42, 25 July 2016RyanmillerOntology Term : 'cancer' added !
87705view09:03, 25 July 2016RyanmillerOntology Term : 'disease pathway' added !
84853view21:49, 28 March 2016Khanspersupdated interactions and refined NICD/HIF1a
84088view05:21, 14 January 2016Khanspersincreased text label size to avoid cutoff text
83871view00:54, 18 December 2015KhanspersModified description
83870view00:54, 18 December 2015KhanspersNew pathway

External references

Datanodes

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NameTypeDatabase referenceComment
HES1GeneProductENSG00000114315 (Ensembl)
HEY1GeneProductENSG00000164683 (Ensembl)
HIF1AGeneProductENSG00000100644 (Ensembl)
HIF1ANGeneProductENSG00000166135 (Ensembl)
MIR148ARnaMI0000253 (miRBase Sequence)
MIR31GeneProductMI0000089 (miRBase Sequence)
VEGFAGeneProductENSG00000112715 (Ensembl)
VEGFBGeneProductENSG00000173511 (Ensembl)
VEGFCGeneProductENSG00000150630 (Ensembl)

Annotated Interactions

No annotated interactions

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