Post-translational modification: gamma carboxylation and hypusine formation (Homo sapiens)

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After translation, many newly formed proteins undergo further covalent modifications that alter their functional properties and that are essentially irreversible under physiological conditions in the body. These modifications include the vitamin K-dependent attachment of carboxyl groups to glutamate residues and the conversion of lysine residues to hypusine.

• Cellular Process
• Homo sapiens