Platelet Aggregation (Plug Formation) (Homo sapiens)
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Curation Tags
Description
The tethering of platelets to the site of vascular injury is the first step in the formation of a platelet thrombus. Firm adhesion of these tethered platelets, as well as the additional recruitment of others onto their surface leads to the formation of large platelet aggregates. The formation of a thrombus is strictly dependent on the formation of interplatelet bonds.
Ontology Tags
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| View all 7... |
| Name | Type | Database reference |
|---|---|---|
| Catecholamine | Metabolite | REACT_17411 (Reactome) ![]() |
| Alpha-2
adrenoceptor | Protein | REACT_18048 (Reactome) ![]() |
| GP1b-IX-V
complex: activated thrombin (factor IIa) | Complex | REACT_24330 (Reactome) ![]() |
| Alpha-2
adrenoceptor: Catecholamine | Complex | REACT_17529 (Reactome) ![]() |
| GPIb-IX-V
complex | Complex | REACT_3007 (Reactome) ![]() |
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