Platelet Aggregation (Plug Formation) (Homo sapiens)

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Curation Tags

Description

The tethering of platelets to the site of vascular injury is the first step in the formation of a platelet thrombus. Firm adhesion of these tethered platelets, as well as the additional recruitment of others onto their surface leads to the formation of large platelet aggregates. The formation of a thrombus is strictly dependent on the formation of interplatelet bonds.

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History

CompareRevisionActionTimeUserComment
42100view21:57, 4 March 2011MaintBotAutomatic update
39910view05:56, 21 January 2011MaintBotNew pathway

External references

View all 7...

Name Type Database reference
Catecholamine MetaboliteREACT_17411 (Reactome)
Alpha-2

adrenoceptor

ProteinREACT_18048 (Reactome)
GP1b-IX-V

complex: activated thrombin (factor IIa)

ComplexREACT_24330 (Reactome)
Alpha-2

adrenoceptor: Catecholamine

ComplexREACT_17529 (Reactome)
GPIb-IX-V

complex

ComplexREACT_3007 (Reactome)
Activated thrombin

(factor IIa)

ComplexREACT_3298 (Reactome)
Integrin alphaIIb

beta3 signaling

PathwayREACT_15523 (Reactome)
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