IL-5 Signaling Pathway (Homo sapiens)

Interleukin-5 belongs to the family of cytokines, which includes IL-3 and GM-CSF. It signals through a receptor complex comprising of an IL-5 receptor alpha subunit (IL5RA), and a common beta chain which is shared between all members of this cytokine family. Binding of IL-5 to IL5RA recruits the beta chain to the complex, this then activates the JAK/STAT and Raf/MAPK signaling modules.

GenMAPP notes 

NetPath 17 - IL-5 Signaling Pathway

NetPath (http://www.netpath.org) is a collaborative project between PandeyLab at Johns Hopkins University (http://pandeylab.igm.jhmi.edu) and the Institute of Bioinformatics (http://www.ibioinformatics.org). If you use this pathway, you must cite the NetPath website until the pathway is published.

GenMAPP remarks 

http://www.netpath.org