1Cell survivalChemotherapyTransporterexpressionImpaired drug expulsionDrug-resistantcancer cellsHCC cellsHOTAIRAK126698ApoptosisP-gpTP53HIF1AWNT6Cell proliferationp21Bcl-xlUCA1linc-RoRMEG3linc-VLDLRMRULG0/G1 cell cycle arrestHypoxiaRecipient cellsEVsEV linc-RoREV linc-VLDLR