NR3C1
Homo sapiens
Cellular Process (WikiPathways-category)
Methylation of NR3C1 gene regulatory sequence was found in individuals that commited suicide and in rats that were treated badly at young age. Higher methylation and and lower glucocortoid receptor expression was confirmed in humans with a "bad youth". See McGowan et al. in Nat Neurosci. 2009. (WikiPathways-description)
Epigenetic Stress Regulation
PubMed
2009
Nat Neurosci
Epigenetic regulation of the glucocorticoid receptor in human brain associates with childhood abuse.
19234457
McGowan PO
Turecki G
Szyf M
Sasaki A
Dymov S
Meaney MJ
Labonte B
D'Alessio AC
Entrez Gene
1958
Entrez Gene
2908
NGFI-A