2932 Entrez Gene 2309 Entrez Gene 5925 Entrez Gene 2308 Entrez Gene IL7R IL7 STAT5A 572 Entrez Gene STAM2 RAF1 JAK3 JAK1 581 Entrez Gene BAX MAP2K1 890 Entrez Gene 1019 Entrez Gene Homo sapiens Interleukin-7 belongs to a family of cytokines, which includes IL-2, IL-4, IL-9, IL-15 and IL-21. It signals through a receptor complex consisting of IL-7 receptor alpha chain (IL7RA) and a common gamma chain (γc) that is shared between all members of this family. IL-7 mainly activates the JAK/STAT signaling module. Source: NetPath http://www.netpath.org/pathways?path_id=NetPath_19 (WikiPathways-description) Cellular Process (WikiPathways-category) NetPath 19 – IL-7 Signaling Pathway The annotation of immune signaling pathways (http://www.netpath.org) is a collaborative project between PandeyLab at Johns Hopkins University (http://pandeylab.igm.jhmi.edu) and the Institute of Bioinformatics (http://www.ibioinformatics.org). If you use these pathways, you must cite these websites. (GenMAPP notes) http://www.netpath.org (GenMAPP remarks) IL-7 Signaling Pathway 1017 Entrez Gene 1213 Entrez Gene 3575 Entrez Gene 5295 Entrez Gene MAPK1 CBL 3718 Entrez Gene 894 Entrez Gene CDK4 AKT1 IL2RG CCND2 3667 Entrez Gene Gene Symbol PTK2B 2185 Entrez Gene 6774 Entrez Gene 6777 Entrez Gene HRAS BLK MAP2K2 CDK2 6776 Entrez Gene STAM 4067 Entrez Gene 10254 Entrez Gene 8027 Entrez Gene 207 Entrez Gene 6772 Entrez Gene SOS1 CBLB 8660 Entrez Gene SHC1 STAT5B RB1 3659 Entrez Gene 4582 Entrez Gene 3265 Entrez Gene 5894 Entrez Gene STAT1 5604 Entrez Gene IRS2 GSK3B 3561 Entrez Gene MUC1 GRB2 IRF1 3716 Entrez Gene 2534 Entrez Gene 5605 Entrez Gene LYN FYN MCL1 10018 Entrez Gene 4170 Entrez Gene BAD MAPK3 FOXO1A 5595 Entrez Gene 640 Entrez Gene 5594 Entrez Gene CLTC FOXO3A 6464 Entrez Gene 868 Entrez Gene BCL2L11 PIK3R1 STAT3 867 Entrez Gene 6654 Entrez Gene CCNA2 2885 Entrez Gene IRS1