Schematic summarizing predicted miR-517a relationships with ARCN1 and USP1.
A genomewide miRNA mimic toxicity screen indicates common and selective vulnerabilities of epithelial ovarian cancer cells. miR-517a targets a common vulnerability, primarily via its target ARCN1.
fb3
26655797
PubMed
A genome-scale screen reveals context-dependent ovarian cancer sensitivity to miRNA overexpression.
Mol Syst Biol
2015
Shields BB
Pecot CV
Gao H
McMillan E
Potts M
Nagel C
Purinton S
Wang Y
Ivan C
Kim HS
Borkowski RJ
Khan S
Rodriguez-Aguayo C
Lopez-Berestein G
Lea J
Gazdar A
Baggerly KA
Sood AK
White MA
regulatory pathwayPW:0000004Pathway Ontology